Prof. Tesio research fields are 1) neuromechanical correlations in balance and gait, 2) neuromechanical correlations in voluntary movement, and 3) statistics and outcome measurement in disability studies. 

Along his career he came across the Institute of Human Physiology of the University of Milan, the Istituto Neurologico “Carlo Besta”, the Geriatric Institute Pio Albergo Trivulzio, the Depts. of Rehabilitation of the teaching hospitals Ospedale San Raffaele in Milan, and the Fondazione Salvatore Maugeri in Pavia.

In his research studies he’s placing special emphasis on the development of original methods of exercise and of diagnosis and assessment of motor impairments, including multifactorial gait analysis, dynamic posturography, isokinetic force measurement, non-invasive electric and magnetic brain stimulation. Typical clinical conditions faced in his research and clinical experience are Multiple Sclerosis, post-stroke syndromes, post-surgical brain and spinal cord lesions, back pain, and complex orthopaedic conditions (e.g. multiple traumas, lower limb amputations and the rotationplasty salvage procedure).

He established international collaborations with researchers from Belgium, France, Israel, UK, US. 

He authored over 100 articles in international Journals, 20 Book chapters, 4 book translations and 2 original books.